Hugo Lloris, the captain, and goalie for Tottenham has a knee injury and will be away for six to eight weeks.
The 36-year-old former France captain suffered a ligament injury in Spurs’ 1-0 Premier League victory over Manchester City on Sunday.
Fraser Forster, a former Southampton player, and England international is a backup for Spurs.
Other options include academy players Brandon Austin and Alfie Whiteman, but neither has much senior-level experience.
Spurs are vying for a Champions League spot for the upcoming season and are currently sixth in the Premier League.
Prior to departing for AC Milan on Tuesday for their first-leg round-of-16 Champions League match, they have a league match against Leicester City on Saturday.
Forster, who joined Spurs on a free transfer in the summer, has only played in one Premier League game for the club—a 2-2 tie with Brentford on Boxing Day.
Lloris retired from international football this month after leading France to the 2018 World Cup title.