The Boston Red Sox and San Francisco Giants will begin a three-game series at 7:10 p.m. ET Friday at Fenway Park. Both teams took a loss in their last game, so they’ll have plenty of motivation to get the W.

The Red Sox fought the good fight in their extra-innings game against the Diamondbacks on Wednesday but wound up with a less-than-desirable result. They fell just short of the Diamondbacks by a score of 7-6.

The Red Sox saw six different players step up and record at least one hit. One of them was Mickey Gasper, who went 1-for-3 while logging a home run and three RBIs. Gasper has been coming through with runners on lately: he’s racked up nine RBIs in his last 12 games compared to five in his previous 25 games.

Meanwhile, the Giants couldn’t handle the Guardians on Thursday and fell 5-2.

Boston is now 68-59, having gone 4-3 since their five-game losing streak ended. As for San Francisco, they have now lost 12 of their last 15 games on the road. That’s put a noticeable dent in their 52-75 record this season.

Boston came up short against San Francisco when the teams last played on June 22, 2025, falling 9-5. Will the Red Sox have more luck at home instead of on the road?

How to Watch San Francisco Giants at Boston Red Sox

• Date: August 21, 2026
• Time: 7:10 p.m. ET
• Venue: Fenway Park
• TV: NESN
• Streaming: Stream on Fubo
• Buy tickets: Buy Giants at Red Sox tickets on Ticketmaster

Probable Starting Pitcher Analysis

Sonny Gray (BOS)

2026 Season Stats: 15-3 | 2.65 ERA | 1.15 WHIP | 7.9 K/9

• Won last start on August 15 @ PIT- 7 IP, 0 ER, 6 H
• 2.65 earned run average this season; 4.28 last season
• Pitching with five days rest
• Last start vs SF (with STL) (September 24, road): (ND) 6 IP, 2 ER, 7 H

Logan Webb (SF)

2026 Season Stats: 8-7 | 3.50 ERA | 1.06 WHIP | 7.1 K/9

• Won last start on August 15 vs. COL- 6 IP, 1 ER, 4 H
• 3-0, 26 IP, 4 ER, 18 H in last four starts; 5-7, 3.98 ERA in prior 18 games
• 7.1 strikeouts per nine innings this season; 9.7 last season
• Last start vs BOS (April 30, 2024, road): (ND) 3.2 IP, 4 ER, 9 H

San Francisco Giants vs. Boston Red Sox Betting Odds

• Moneyline: SF +153 / BOS -185
• Run line: BOS -1.5
• Over/Under: 7.5

Betting lines as of 08/21/2026 at 8:28 AM ET. Odds subject to change. Bet with bet365.

San Francisco Giants Stat Check: Who’s Hot, Who’s Not

Who’s Hot

• Willy Adames (SF): 1+ time on base in 13 straight games

Who’s Not

• Drew Gilbert (SF) Previous Game: 0-3, 3 K
  • 1-12 in last four games; .243/.330/.376 in prior 95 games
• Victor Bericoto (SF): .143/.143/.143 in last eight games; .314/.327/.608 in prior 19 games
• Grant McCray (SF): 0-12 in last four games; .120/.290/.240 in prior 12 games

Boston Red Sox Stat Check: Who’s Hot, Who’s Not

Who’s Hot

• Wilyer Abreu (BOS): 1+ time on base in 16 straight games
• Nick Sogard (BOS): 6-12, 1 HR in last three games; .240/.353/.310 in prior 28 games
• Willson Contreras (BOS): 6-13, 3 RBIs and four runs in last three games; .278/.389/.523 in prior 112 games

Who’s Not

• Ceddanne Rafaela (BOS) Previous Game: 0-5, 2 K
  • No walks in 13 straight games
• Andruw Monasterio (BOS) Previous Game: 0-4
  • 2-16 in last four games; .270/.332/.444 in prior 80 games
• Adley Rutschman (BOS): .161/.316/.290 in last nine games; .255/.333/.440 in prior 66 games

Last 10 Games for San Francisco Giants (3-7)

• Aug. 20: L @ CLE 2-5
• Aug. 19: W @ CLE 1-0
• Aug. 18: L @ CLE 1-8
• Aug. 16: L vs. COL 7-13
• Aug. 15: W vs. COL 7-1
• Aug. 14: L vs. COL 2-5
• Aug. 12: L vs. HOU 1-2
• Aug. 11: W vs. HOU 4-1
• Aug. 10: L vs. HOU 3-6
• Aug. 9: L vs. DET 1-3

Last 10 Games for Boston Red Sox (4-6)

• Aug. 19: L vs. AZ 6-7
• Aug. 18: W vs. AZ 9-4
• Aug. 17: W vs. AZ 11-1
• Aug. 16: L @ PIT 3-8
• Aug. 15: W @ PIT 4-0
• Aug. 14: L @ PIT 4-8
• Aug. 13: W @ TOR 7-0
• Aug. 12: L @ TOR 4-6
• Aug. 11: L @ TOR 3-5
• Aug. 10: L @ TOR 1-2

Final Score Prediction for San Francisco Giants @ Boston Red Sox on August 21, 2026

Giants 4 – Red Sox 3

Lean: Giants

That’s a slight lean against the line, but we like the Giants in this one, and we like Logan Webb to build on his last start.

Disclosure: Some or all of this content may have been generated by AI. While we strive for accuracy, AI can occasionally produce incorrect information. If you buy something via one of our links, we may earn a commission.